South Jefferson will be the second seed in Class D as the Section 3 girls lacrosse brackets were released Sunday afternoon.
South Jefferson (15-1) will host seventh-seeded Clinton (9-5) in a quarterfinal matchup at 6 p.m. Tuesday.
Skaneateles (12-0) is the top-seeded team.
General Brown (7-5) is fifth seeded and will play at No. 4 Marcellus (5-7) in a Tuesday quarterfinal.
In Class B, third-seeded Watertown (10-3) travels to No. 2 Fayetteville-Manlius (3-12) in a semifinal at 5 p.m. Thursday.
Indian River (7-7) is fifth seed in Class C and will go to No. 4 New Hartford (9-3) in an opening-round game slated for 5 p.m. Tuesday. The winner will take on top-seeded Fulton (11-2) in a semifinal Thursday.
The sectional tournaments are set to finish up Saturday, with times and locations to be determined.